Given the risk of health consequences associated with Whole Body Vibration (WBV), the International Standards Organization (ISO) has published several guidelines on levels of vibration exposure and their relationship to health outcomes. Specifically, ISO 2631 defines WBV exposure from a seated position. Researchers across many disciplines use the ISO 2631 standards as a framework for analyzing exposure to vibration.

In studies that have investigated vibration exposure among manual wheelchair users, it has been found that current wheelchair frames are not sufficient in reducing “Whole Body Vibration”. Loopwheels have been shown to help with this: even at slow speeds, ie when propelling manually, Loopwheels help reduce vibrations through the wheelchair frame.